Cell-free DNA screening
Abbreviation: cfDNA
Cell-free DNA (cfDNA) screening is another name for NIPT. During pregnancy, small fragments of DNA from the placenta enter your bloodstream. A blood sample is taken from you and analysed in a laboratory to look at these fragments for signs of chromosomal abnormalities. The test can be done from 10 weeks and is considered far more accurate than older combined first trimester screening for conditions like Down syndrome. Results are usually returned within one to two weeks. Because it looks at placental DNA rather than the baby's DNA directly, rare false positives and false negatives can occur.
What This Means for You
Understanding Cell-free DNA screening is an important part of your 10+ weeks journey. During pregnancy, your care team will use this term regularly. Being familiar with it means you can ask better questions and feel more confident at your antenatal appointments.
Explore our Pregnancy hubGood to Know
cfDNA screening and NIPT refer to the same test and are used interchangeably by Singapore hospitals and labs. If your doctor recommends NIPT, they are referring to this technology.
Related Terms
Source: https://www.acog.org/womens-health/dictionary
Always consult your healthcare provider for personalised advice.
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