Pregnancy Pregnancy/postpartum Also: Rhogam

Rho(D) immune globulin

Abbreviation: Rhogam

Rho(D) immune globulin is an injection given to Rh-negative pregnant women to prevent their immune system from reacting to Rh-positive fetal blood cells. It works by clearing any fetal Rh-positive cells from the mother's circulation before her body can form antibodies against them. It is typically given around 28 weeks of pregnancy, and again within 72 hours after birth if the baby is confirmed Rh positive. It is also given after events such as miscarriage, amniocentesis, or vaginal bleeding during pregnancy. The brand name RhoGAM is commonly used, though other formulations exist. This injection is highly effective at preventing Rh sensitization.

What This Means for You

Understanding Rho(D) immune globulin is an important part of your pregnancy/postpartum journey. During pregnancy, your care team will use this term regularly. Being familiar with it means you can ask better questions and feel more confident at your antenatal appointments.

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Good to Know

In Singapore public hospitals such as KKH and NUH, Rho(D) immune globulin is offered as part of standard antenatal care for Rh-negative mothers. Do not skip the postnatal dose even if you feel well, as the timing is critical for protecting future pregnancies.

Source: https://www.acog.org/womens-health/dictionary

Always consult your healthcare provider for personalised advice.

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Medical Disclaimer: This glossary is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional for diagnosis and treatment.

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